Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SPOP | O43791 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949607 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL3949605 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL10429508 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL4048939 | 0.77 | KDM4E (0.30) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL4048933 | 0.77 | KDM4E (0.30) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL11130790 | 0.77 | NR1I2 (0.32) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL1387526 | 0.73 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL3188369 | 0.73 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL8590684 | 0.73 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL1387528 | 0.73 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9278778-A | — | — | None | — | — | JP | disclosed |
| EP-0882052-A1 | NEW CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| JP-H09278778-A | ANTI-MRSA CEPHALOSPORIN COMPOUND | KYORIN PHARMACEUT CO LTD | 1997-10-28 | — | — | JP | disclosed |
| EP-0796263-A1 | CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997029111-A1 | NEW CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-14 | — | — | WO | disclosed |
| WO-1996017850-A1 | CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-13 | — | — | WO | disclosed |
| EP-0057422-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4066641-A | METHOD FOR CYCLIZATION TO GIVE CEPHEM RING | HAMASHIMA YOSHIO | 1978-01-03 | — | — | US | disclosed |