Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944306 | 0.78 | GBA1 (0.46) | GBA1CHRNB4CHRNA3 | |
| SCHEMBL6944308 | 0.78 | GBA1 (0.46) | GBA1CHRNB4CHRNA3 | |
| SCHEMBL7678641 | 0.78 | GBA1 (0.46) | GBA1CHRNB4CHRNA3 | |
| SCHEMBL7680047 | 0.75 | HTR3E (0.39) | CHRNB4CHRNA3 | |
| SCHEMBL6941357 | 0.75 | HTR3E (0.39) | CHRNB4CHRNA3 | |
| SCHEMBL7243838 | 0.74 | CHRNB2 (0.45) | CHRNA3 | |
| SCHEMBL6941249 | 0.72 | CHRNB4 (0.36) | CHRNB4CHRNA3 | |
| SCHEMBL7235453 | 0.69 | CHRNA7 (0.50) | CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL5672686 | 0.69 | CHRNB4 (0.42) | GBA1CHRNB4CHRNA3 | |
| SCHEMBL4577960 | 0.69 | GBA1 (0.55) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2072178-A | — | — | None | — | — | JP | disclosed |
| JP-H0272178-A | CHEMICAL INTERMEDIATE | BEECHAM GROUP PLC | 1990-03-12 | — | — | JP | disclosed |