Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799464 | 0.92 | THRA (0.56) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL10420324 | 0.92 | TSHR (0.62) | TSHRTP53ALDH1A1PLA2G4BRARB | |
| SCHEMBL9217693 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9222326 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9217735 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9219378 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9222151 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9226486 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9219869 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B | |
| SCHEMBL9226574 | 0.89 | TSHR (0.51) | TSHRTHRATP53ALDH1A1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2049754-A | — | — | None | — | — | JP | disclosed |
| JP-H0249754-A | NAPHTHALENE COMPOUND LIQUID CRYSTAL COMPOSITION CONTAINING SAID COMPOUND | MITSUI PETROCHEM IND LTD | 1990-02-20 | — | — | JP | disclosed |