Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799447 | 0.94 | NPC1 (0.53) | THRATSHRTP53ALDH1A1 | |
| SCHEMBL9799611 | 0.92 | TSHR (0.54) | THRATSHRTP53PLA2G4BRARB | |
| SCHEMBL9779497 | 0.92 | TSHR (0.54) | THRATSHRTP53PLA2G4BRARB | |
| SCHEMBL9799608 | 0.92 | TSHR (0.54) | THRATSHRTP53PLA2G4BRARB | |
| SCHEMBL10429590 | 0.92 | TSHR (0.53) | THRATSHRTP53ALDH1A1PLA2G4B | |
| SCHEMBL9458305 | 0.91 | ALDH1A1 (0.57) | THRATSHRALDH1A1 | |
| SCHEMBL9458665 | 0.91 | ALDH1A1 (0.57) | THRATSHRALDH1A1 | |
| SCHEMBL9222151 | 0.90 | TSHR (0.51) | THRATSHRTP53ALDH1A1PLA2G4B | |
| SCHEMBL9217693 | 0.90 | TSHR (0.51) | THRATSHRTP53ALDH1A1PLA2G4B | |
| SCHEMBL9219869 | 0.90 | TSHR (0.51) | THRATSHRTP53ALDH1A1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061399-A | FERROELECTRICITY | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1991-10-29 | — | — | US | disclosed |
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |
| EP-0302875-A1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM. | SECR DEFENCE BRIT (GB) | 1989-02-15 | — | — | EP | disclosed |
| WO-1987006577-A2 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1987-11-05 | — | — | WO | disclosed |