Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.35 |
| ▸ | CNR1 | P21554 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429854 | 1.00 | CNR2 (0.35) | CNR2CNR1SLC6A4SLC6A3MEN1 | |
| SCHEMBL10429749 | 1.00 | CNR2 (0.35) | CNR2CNR1SLC6A4SLC6A3MEN1 | |
| SCHEMBL8962875 | 0.79 | CNR2 (0.34) | CNR2CNR1SLC6A4SLC6A3CETP | |
| SCHEMBL8962723 | 0.79 | CNR2 (0.34) | CNR2CNR1SLC6A4SLC6A3CETP | |
| SCHEMBL11028664 | 0.74 | SLC6A4 (0.37) | CNR2CNR1SLC6A4SLC6A3CETP | |
| SCHEMBL10429831 | 0.74 | SLC6A4 (0.34) | CNR2CNR1SLC6A4SLC6A3CETP | |
| SCHEMBL1575027 | 0.74 | BCHE (0.39) | SLC6A4SLC6A3MEN1TP53CYP3A4 | |
| SCHEMBL9359639 | 0.71 | SLC6A3 (0.43) | CNR2CNR1SLC6A4SLC6A3CETP | |
| SCHEMBL8931548 | 0.71 | SLC6A3 (0.43) | CNR2CNR1SLC6A4SLC6A3CETP | |
| SCHEMBL8963206 | 0.70 | CNR1 (0.37) | CNR2CNR1SLC6A4SLC6A3CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400068-A1 | DERIVATIVES OF 2,3-DIFLUOROPHENOL | MERCK PATENT GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |
| WO-1989008632-A1 | DERIVATIVES OF 2,3-DIFLUOROPHENOL | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |