Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962723 | 1.00 | CNR2 (0.34) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL10429684 | 0.79 | CNR2 (0.35) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL10429854 | 0.79 | CNR2 (0.35) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL10429749 | 0.79 | CNR2 (0.35) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL8963206 | 0.72 | CNR1 (0.37) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL11028664 | 0.71 | SLC6A4 (0.37) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL9333940 | 0.69 | CNR1 (0.38) | CNR2CNR1CETPSLC6A4SLC6A3 | |
| SCHEMBL9300105 | 0.69 | CNR2 (0.36) | CNR2CNR1SLC6A4SLC6A3 | |
| SCHEMBL1575027 | 0.68 | BCHE (0.39) | SLC6A4SLC6A3 | |
| SCHEMBL8931548 | 0.68 | SLC6A3 (0.43) | CNR2CNR1CETPSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |