SCHEMBL10429706

SCHEMBL10429706

CCCCCC1(O)C=CC(c2ccc(-c3ccccc3)cc2F)=CC1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.35
RARA P10276 2/20 0.35
RARG P13631 1/20 0.35
CNR2 P34972 9/20 0.34
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MGLL Q99685 1/20 0.32
CNR1 P21554 2/20 0.32
ESR2 Q92731 2/20 0.32
PDK2 Q15119 1/20 0.31
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29137826 0.85 RARB (0.33) RARBRARARARGCNR2MMP2
SCHEMBL10429822 0.83 RARB (0.37) RARBRARARARGCNR2MMP2
SCHEMBL9852460 0.81 OPRM1 (0.39) MMP2MMP9OPRM1OPRD1OPRK1
SCHEMBL28596887 0.78 OPRM1 (0.36) MMP2MMP9ESR2OPRM1OPRD1
SCHEMBL10429834 0.78 ALOX5AP (0.31) RARBRARARARGMMP2MMP9
SCHEMBL10429741 0.76 NR5A2 (0.30)
SCHEMBL9494148 0.73 MMP2 (0.36) RARBMMP2MMP9
SCHEMBL9492805 0.73 MMP2 (0.36) RARBMMP2MMP9
SCHEMBL9494043 0.73 MMP2 (0.36) RARBMMP2MMP9
SCHEMBL9494696 0.73 MMP2 (0.36) RARBMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360042-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed