SCHEMBL1042982

SCHEMBL1042982

C=CCOC(=O)C(C(C)=O)C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 4/20 0.41
CYP3A4 P08684 3/20 0.39
MAPT P10636 3/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.32
USP2 O75604 2/20 0.32
LMNA P02545 1/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
SNCA P37840 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10830642 0.95 TDP1 (0.42) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL7690118 0.90 TDP1 (0.39) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL14745750 0.85 CYP3A4 (0.45) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL5065076 0.85 MAPT (0.36) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL5227209 0.80 TDP1 (0.41) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL6483817 0.80 TDP1 (0.44) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL2036556 0.78 TDP1 (0.40) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL2524519 0.78 TDP1 (0.40) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL4766772 0.77 TSHR (0.42) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL5054327 0.77 TDP1 (0.42) TDP1TSHRCYP3A4MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5569703-A COPOLYMER OF ETHYLENE-VINYL ESTER AND AN ACETOACETYL GROUP CONTAINING COPOLYMERIZABLE UNIT; WATER RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-29 US claimed
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP claimed
EP-0602027-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES. EUROP COLOUR PLC (GB) 1994-06-22 EP claimed
WO-1992001664-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROPEAN COLOUR PLC (GB) 1992-02-06 WO claimed
US-20230265041-A1 CURCUMIN ANALOGUES AS ZINC CHELATORS AND TEHIR USES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-24 US disclosed
US-11608309-B2 Curcumin analogues as zinc chelators and their uses THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-03-21 US disclosed
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
CN-114981319-A Polyvinyl alcohol resin, method for producing polyvinyl alcohol resin, dispersant, and dispersant for suspension polymerization 三菱化学株式会社 2022-08-30 CN disclosed
US-11329288-B2 Secondary battery negative electrode binder composition, secondary battery negative electrode, and secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-10 US disclosed
EP-3936532-A1 POLYVINYL ALCOHOL-BASED RESIN, METHOD FOR PRODUCING POLYVINYL ALCOHOL-BASED RESIN, DISPERSING AGENT AND DISPERSING AGENT FOR SUSPENSION POLYMERIZATION Mitsubishi Chemical Corporation (JP) 2022-01-12 EP disclosed
US-20210395409-A1 POLYVINYL ALCOHOL-BASED RESIN, METHOD FOR PRODUCING POLYVINYL ALCOHOL-BASED RESIN, DISPERSING AGENT AND DISPERSING AGENT FOR SUSPENSION POLYMERIZATION MITSUBISHI CHEMICAL CORPORATION (JP) 2021-12-23 US disclosed
EP-3904396-A1 DIVERTING AGENT AND METHOD FOR CLOSING CRACK IN WELL USING SAME Mitsubishi Chemical Corporation (JP) 2021-11-03 EP disclosed
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP disclosed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US disclosed
EP-0602027-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES. EUROP COLOUR PLC (GB) 1994-06-22 EP disclosed
WO-1992001664-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROPEAN COLOUR PLC (GB) 1992-02-06 WO disclosed
US-4560724-A ADDITION POLYMERIZATION, PEROXIDE INITIATORS, STARCHES, SULFUR-CONTAINING REDUCING AGENTS WACKER-CHEMIE GMBH (DE) 1985-12-24 US disclosed
US-4532295-A Polymerizing in presence of starch derivative and water soluble peroxide free radical initiator WACKER-CHEMIE GMBH (DE) 1985-07-30 US disclosed
US-4365040-A BINDERS FOR PAINTS OR LACQUERS WACKER-CHEMIE GMBH (DE) 1982-12-21 US disclosed
US-4365040-A BINDERS FOR PAINTS OR LACQUERS WACKER-CHEMIE GMBH (DE) 1982-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265041-A1 CURCUMIN ANALOGUES AS ZINC CHELATORS AND TEHIR USES NFRKB, NFKBIA, NFKB1 TDP1 2950/4885TSHR 489/4885CYP3A4 3781/4885
US-11608309-B2 Curcumin analogues as zinc chelators and their uses NFKBIA, NFKB1, NFKB2 TDP1 3035/4885TSHR 2690/4885CYP3A4 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.