Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830642 | 0.90 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL1042982 | 0.90 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL14745750 | 0.80 | CYP3A4 (0.45) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL5065076 | 0.79 | MAPT (0.36) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL440465 | 0.75 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL3459899 | 0.75 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL6483817 | 0.75 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL5227209 | 0.75 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL1012864 | 0.74 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL2524519 | 0.73 | TDP1 (0.40) | TDP1TSHRCYP3A4MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956456-B | Preparation method of reversible cross-linking water-soluble polyester with side chain containing sulfhydryl group | 大连理工常熟研究院有限公司 | 2023-09-05 | — | — | CN | claimed |
| US-6384228-B2 | EPIBATIDINE; ANALGESICS; ANIMAL EXTRACTS | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| US-20020010339-A1 | METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-01-24 | — | — | US | disclosed |
| US-4565879-A | Process for producing substituted pyrroles | ETHYL CORPORATION (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0089392-A1 | Process for producing substituted pyrroles | ETHYL CORPORATION (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4374255-A | BY REACTION OF A CHLOROMETHYL LOWERALKYL KETONE, A DILOWERALKYL ACETONE DICARBOXYLATES AND AN AMINE IN THE PRESENCE OF A LOWER ALKANOL | ETHYL CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |
| WO-1982002044-A1 | PREPARATION OF PYRROLE ESTERS | ETHYL CORP (US) | 1982-06-24 | — | — | WO | disclosed |
| EP-0054428-A1 | Preparation of pyrrole esters | ETHYL CORPORATION (US) | 1982-06-23 | — | — | EP | disclosed |
| US-4333878-A | MAKING 1,4-DIALKYLPYRROLE DIESTERS FROM 2-HYDROCARBOXY-1-NITROALKANE AND ENAMINE OF DIALKYL ACETONE DICARBOXYLATE | ETHYL CORPORATION (US) | 1982-06-08 | — | — | US | disclosed |
| WO-1982001552-A1 | PROCESS FOR PRODUCING SUBSTITUTED PYRROLES | ETHYL CORP (US) | 1982-05-13 | — | — | WO | disclosed |
| EP-0051442-A1 | Process for producing substituted pyrroles | ETHYL CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |
| US-3963775-A | FROM KETENE AND PHOSGENE | AKZONA INCORPORATED (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010339-A1 | METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF | DHPS, ALAD, HAAO | TDP1 3149/4885TSHR 4144/4885CYP3A4 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.