Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481498 | 1.00 | LMNA (0.64) | LMNATSHRPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL1038937 | 0.94 | LMNA (0.66) | LMNATSHRPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8486883 | 0.94 | LMNA (0.66) | LMNATSHRPDE4APDE4BPDE4C | |
| SCHEMBL4958108 | 0.93 | PDE4A (0.69) | LMNATSHRPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL4955764 | 0.91 | PDE4A (0.67) | LMNATSHRPDE4APDE4BPDE4C | |
| SCHEMBL11501103 | 0.91 | PDE4A (0.70) | LMNATSHRPDE4APDE4BPDE4C | |
| SCHEMBL4958962 | 0.89 | PDE4A (0.70) | LMNATSHRPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL4956228 | 0.88 | PDE4A (0.69) | LMNATSHRPDE4APDE4BPDE4C | |
| SCHEMBL14259780 | 0.86 | TSHR (0.64) | LMNATSHRPDE4APDE4BPDE4C | |
| SCHEMBL1037717 | 0.86 | PDE4A (0.60) | LMNATSHRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903344-B1 | Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin | SHISEIDO CO LTD (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-5972929-A | Quinazolinone derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0903344-A1 | Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin | SHISEIDO COMPANY LIMITED (JP) | 1999-03-24 | — | — | EP | disclosed |