SCHEMBL10429837

SCHEMBL10429837

Cc1ccc(C(CCN(C)C)CCN(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.47
HRH1 P35367 1/20 0.47
CHRNA7 P36544 1/20 0.46
UTS2R Q9UKP6 12/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5463519 0.79 UTS2R (0.46) HTR2AHRH1CHRNA7UTS2R
SCHEMBL5459280 0.79 HTR2A (0.44) HTR2AHRH1CHRNA7UTS2R
SCHEMBL9856676 0.79 HTR2A (0.53) HTR2AHRH1UTS2R
Tolpropamine SCHEMBL29300 0.78 HRH1 (0.81) HTR2AHRH1UTS2R
SCHEMBL10620559 0.77 CHRNA7 (0.50) HTR2AHRH1CHRNA7
Tolpropamine SCHEMBL4193587 0.76 HRH1 (0.78) HTR2AHRH1UTS2R
SCHEMBL20757029 0.75 CHRNA7 (0.36) CHRNA7
Tolpropamine SCHEMBL1651656 0.75 HRH1 (0.75) HTR2AHRH1UTS2R
SCHEMBL18613186 0.75 ESR1 (0.48) CHRNA7
SCHEMBL28588039 0.74 HTR2A (0.48) HTR2AHRH1CHRNA7UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4980067-A Separation of microorganisms CUNO, INC. (US) 1990-12-25 US disclosed