SCHEMBL10429896

SCHEMBL10429896

CCCCC1CCC2(CC1)OCC(CN1CC(C)CC(C)C1)O2

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
HTR1A P08908 9/20 0.36
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
ADRA1B P35368 8/20 0.33
ADRA1A P35348 7/20 0.33
ADRA1D P25100 7/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9426043 0.93 GAA (0.40) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL8126482 0.81 GAA (0.41) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL8996692 0.79 GAA (0.39) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL12676408 0.72 CYP1A2 (0.34) GAACYP1A2
SCHEMBL919052 0.70 CYP1A2 (0.33) CYP1A2
SCHEMBL10487093 0.68 GAA (0.41) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL10487144 0.68 GAA (0.44) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL11170793 0.68 ALDH1A1 (0.33) GAACYP1A2
SCHEMBL9426913 0.68 GAA (0.41) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL9426648 0.67 GAA (0.42) GAAHTR1ATMEM97SIGMAR1ADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2108685-A None JP disclosed
JP-H02108685-A AMINOMETHYL HETEROCYCLIC COMPOUND, ITS PRODUCTION, USE OF THE SAME FOR PESTCONTROL AND NOVEL INTERMEDIATE BAYER AG 1990-04-20 JP disclosed