Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 10/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9547996 | 0.84 | PTGS2 (0.50) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451959 | 0.81 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451876 | 0.80 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451865 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451943 | 0.79 | MAPT (0.49) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451931 | 0.78 | PTGS2 (0.58) | MAPTALDH1A1KDM4EGAALMNA | |
| Hydrochloric Acid SCHEMBL9547998 | 0.78 | MAPT (0.68) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451908 | 0.76 | MAPT (0.50) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9452021 | 0.76 | PTGS2 (0.56) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451935 | 0.76 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | claimed |