Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303393 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5811390 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5303634 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5288511 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5308593 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5289382 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5289880 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5289310 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5306421 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL5295844 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304379-B2 | Silicon compound-containing solidified detergent composition and method for producing the same | HIROSHIMA UNIVERSITY (JP) | 2012-11-06 | — | — | US | claimed |
| US-20110172183-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT ARTICLE OBTAINED BY THE METHOD | HIROSHIMA UNIVERSITY (JP) | 2011-07-14 | — | — | US | claimed |
| CN-102105062-A | Method of fixing antibacterial agent and article obtained by the method | UNIV HIROSHIMA | 2011-06-22 | — | — | CN | claimed |
| EP-2274985-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT AND ARTICLE OBTAINED BY THE METHOD | Hiroshima University (JP) | 2011-01-19 | — | — | EP | claimed |
| US-20100190683-A1 | SOLIDIFIED DETERGENT COMPOSITIONS AND METHOD FOR PRODUCING THE SAME | HIROSHIMA UNIVERSITY (JP) | 2010-07-29 | — | — | US | claimed |
| EP-2186873-A1 | SOLIDIFIED DETERGENT COMPOSITION AND METHOD FOR PRODUCING THE SAME | Hiroshima University (JP) | 2010-05-19 | — | — | EP | claimed |
| CN-107006510-B | Method for immobilizing antibacterial agent and method for immobilizing antiviral agent | 国立大学法人广岛大学 | 2023-01-03 | — | — | CN | disclosed |
| EP-2377400-B1 | ANTIBACTERIAL COMPOSITION CONTAINING SILICON-CONTAINING COMPOUND, MOUTH CLEANING | UNIV HIROSHIMA (JP) | 2021-03-03 | — | — | EP | disclosed |
| US-9278107-B2 | Antibacterial agent composition and antiviral agent composition comprising silicon-containing compound; antibacterializing method, cleaning/mouth rinsing method; method for fixing antibacterial agent and antiviral agent | HIROSHIMA UNIVERSITY (JP) | 2016-03-08 | — | — | US | disclosed |
| US-8859009-B2 | Method of fixing antibacterial agent and article obtained by the method | HIROSHIMA UNIVERSITY (JP) | 2014-10-14 | — | — | US | disclosed |
| US-8304379-B2 | Silicon compound-containing solidified detergent composition and method for producing the same | HIROSHIMA UNIVERSITY (JP) | 2012-11-06 | — | — | US | disclosed |
| CN-102333446-A | Antibacterial agent composition and antiviral agent composition containing silicon-containing compound, and antibacterial method, cleaning method, gargling method, antibacterial agent and antiviral agent immobilizing method | UNIV HIROSHIMA | 2012-01-25 | — | — | CN | disclosed |
| US-20110293542-A1 | ANTIBACTERIAL AGENT COMPOSITION AND ANTIVIRAL AGENT COMPOSITION COMPRISING SILICON-CONTAINING COMPOUND; ANTIBACTERIALIZING METHOD, CLEANING/MOUTH RINSING METHOD; METHOD FOR FIXING ANTIBACTERIAL AGENT AND ANTIVIRAL AGENT | HIROSHIMA UNIVERSITY (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-2377400-A1 | ANTIBACTERIAL COMPOSITION AND ANTIVIRAL COMPOSITION EACH CONTAINING SILICON-CONTAINING COMPOUND, ANTIBACTERIALIZING METHOD, CLEANING/MOUTH CLEANING METHOD, AND METHOD FOR IMMOBILIZING ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT | Hiroshima University (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-20110172183-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT ARTICLE OBTAINED BY THE METHOD | HIROSHIMA UNIVERSITY (JP) | 2011-07-14 | — | — | US | disclosed |
| CN-102105062-A | Method of fixing antibacterial agent and article obtained by the method | UNIV HIROSHIMA | 2011-06-22 | — | — | CN | disclosed |
| EP-2274985-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT AND ARTICLE OBTAINED BY THE METHOD | Hiroshima University (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20100190683-A1 | SOLIDIFIED DETERGENT COMPOSITIONS AND METHOD FOR PRODUCING THE SAME | HIROSHIMA UNIVERSITY (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2186873-A1 | SOLIDIFIED DETERGENT COMPOSITION AND METHOD FOR PRODUCING THE SAME | Hiroshima University (JP) | 2010-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172183-A1 | METHOD OF FIXING ANTIBACTERIAL AGENT ARTICLE OBTAINED BY THE METHOD | FBL, AOC1, CDC20 | ALDH1A1 3476/4885TP53 3952/4885CYP3A4 2915/4885 |
| US-20110293542-A1 | ANTIBACTERIAL AGENT COMPOSITION AND ANTIVIRAL AGENT COMPOSITION COMPRISING SILICON-CONTAINING COMPOUND; ANTIBACTERIALIZING METHOD, CLEANING/MOUTH RINSING METHOD; METHOD FOR FIXING ANTIBACTERIAL AGENT AND ANTIVIRAL AGENT | SEM1, LSM14A, SSRP1 | ALDH1A1 2204/4885TP53 3238/4885CYP3A4 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.