CDC20 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL28455540	0.67	2/20
SCHEMBL17264260	0.72	1/20
SCHEMBL17265825	0.65	1/20
SCHEMBL28462602	0.60	1/20
SCHEMBL28457230	0.59	1/20
SCHEMBL28464591	0.57	1/20
SCHEMBL23355108	0.53	1/20
SCHEMBL31031196	0.50	1/20
SCHEMBL12106518	0.49	1/20
SCHEMBL12109762	0.49	1/20
SCHEMBL12103388	0.48	1/20
SCHEMBL28937287	0.48	1/20
SCHEMBL21967470	0.47	1/20
SCHEMBL1667195	0.47	1/20
SCHEMBL11913958	0.47	1/20
SCHEMBL29256804	0.46	1/20
SCHEMBL5840311	0.45	1/20
SCHEMBL17079909	0.45	1/20
SCHEMBL3391799	0.42	1/20

Clinical trials — most relevant to CDC20 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt	PHASE4	COMPLETED
Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE)	PHASE1/PHASE2	NOT_YET_RECRUITING
Abemaciclib With or Without Atezolizumab for mCRPC	PHASE2	COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer	PHASE2	COMPLETED
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers	PHASE1/PHASE2	COMPLETED
TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone in Metastatic Castration-Resistant Prostate Cancer	PHASE2	UNKNOWN
Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction	PHASE2	ACTIVE_NOT_RECRUITING
AZD1775 for Advanced Solid Tumors	PHASE1	COMPLETED
Phase I Study to Assess the Safety, Pharmacokinetics, & Pharmacodynamics of GSK923295 in Subjects w/ Refractory Cancer	PHASE1	COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors	PHASE1	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel	PHASE1	COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
A Clinical Trial of CNCT19 Cells in the Treatment of CD19 Positive Relapsed or Refractory Diffuse Non-Hodgkin Lymphoma	PHASE1	COMPLETED
A Clinical Study of TQB3824 in Subjects With Advanced Cancer	PHASE1	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer	nan	UNKNOWN
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
HCCBloodTest for Detection of Hepatocellular Carcinoma (HCC)	nan	COMPLETED
Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism	nan	UNKNOWN
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED
Study of the Effect of Innate on the Inflammatory Response to Endotoxin	nan	RECRUITING
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome	nan	RECRUITING
Role of Geminin and Mcm-2 in Prognosis of Renal Cell Carcinoma	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Molecular Analysis in Tissue Samples From Patients With Advanced or Metastatic Neuroendocrine Tumors	nan	UNKNOWN
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Unusual Infiltrative Patterns of Malignant Cells in Endometrial Carcinoma and Immunohistochemical Expression of P53	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a CDC20 binder may also engage these)

Protein	Name	Similarity
Q9JJ66	—	1.000	Q9JJ66 →
Q62623	—	1.000	Q62623 →
Q9S7I8	—	1.000	Q9S7I8 →
Q9R1K5	—	0.998	Q9R1K5 →
Q5H7C0	—	0.998	Q5H7C0 →
Q9UM11	—	0.995	Q9UM11 →
A0A396ISC0	—	0.991	A0A396ISC0 →
Q4PSE4	—	0.991	Q4PSE4 →
Q9SZA4	—	0.990	Q9SZA4 →
Q3E906	—	0.989	Q3E906 →
Q9S7H3	—	0.986	Q9S7H3 →
Q92828	—	0.985	Q92828 →
O00423	—	0.983	O00423 →
Q8LPL5	—	0.983	Q8LPL5 →
Q8VZS9	—	0.981	Q8VZS9 →
Q8C0P5	—	0.980	Q8C0P5 →
Q4V8C3	—	0.979	Q4V8C3 →
P70218	—	0.979	P70218 →
Q7ZXX9	—	0.978	Q7ZXX9 →
Q8CFD5	—	0.978	Q8CFD5 →
Q9BVA0	—	0.977	Q9BVA0 →
P58404	—	0.977	P58404 →
O95834	—	0.977	O95834 →
Q5XI13	—	0.977	Q5XI13 →
Q9SXY1	—	0.977	Q9SXY1 →
Q7T0W1	—	0.976	Q7T0W1 →
Q6P6T4	—	0.976	Q6P6T4 →
Q32P44	—	0.976	Q32P44 →
Q5VU92	—	0.976	Q5VU92 →
Q32LP9	—	0.976	Q32LP9 →