Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9148686 | 1.00 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9142802 | 1.00 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL10430870 | 1.00 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9144976 | 1.00 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL10430758 | 1.00 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9148420 | 0.98 | HSP90AA1 (0.56) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9145384 | 0.81 | HDAC3 (0.52) | HSP90AA1MEN1KMT2AMAPK1CES2 | |
| SCHEMBL10481745 | 0.77 | HSP90AA1 (0.70) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL19359738 | 0.77 | HSP90AA1 (0.70) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL8497574 | 0.77 | HSP90AA1 (0.70) | HSP90AA1FAAHMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395075-A2 | Liquid catalyst component, catalyst system containing the same, and process for producing ethylene-alpha-olefin copolymers using the catalyst system | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |