Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922933 | 0.79 | MAPT (0.54) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL7922930 | 0.79 | MAPT (0.54) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL29139875 | 0.78 | MAPT (0.53) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL27959814 | 0.76 | MAPT (0.54) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL1489046 | 0.76 | MAPT (0.54) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL9006476 | 0.75 | MAPT (0.69) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL7101080 | 0.74 | MAPT (0.58) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL28383313 | 0.74 | MAPT (0.58) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL29843588 | 0.74 | MAPT (0.58) | MAPTNPC1RAB9ABCHELMNA | |
| SCHEMBL4260029 | 0.72 | AKR1C3 (0.42) | PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |