Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489046 | 0.85 | MAPT (0.54) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL27959814 | 0.85 | MAPT (0.54) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL9006476 | 0.80 | MAPT (0.69) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL8211218 | 0.78 | CA2 (0.54) | CA1CA2CA4CA9 | |
| SCHEMBL8211221 | 0.78 | CA2 (0.54) | CA1CA2CA4CA9 | |
| SCHEMBL10431020 | 0.78 | MAPT (0.50) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL626787 | 0.78 | MAPT (0.75) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL29420130 | 0.78 | MAPT (0.75) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL10893208 | 0.78 | MAPT (0.75) | MAPTBCHERAB9ALMNANPC1 | |
| SCHEMBL626785 | 0.78 | MAPT (0.75) | MAPTBCHERAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229181-A | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117180248-A | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-08 | — | — | CN | disclosed |