Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.62 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12301533 | 0.87 | SLC7A5 (0.65) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL3499880 | 0.85 | SLC7A5 (0.63) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL7384982 | 0.85 | SLC7A5 (0.63) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL14415228 | 0.84 | SLC7A5 (0.59) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL4928282 | 0.84 | LOXL2 (0.69) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL30694681 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL127411 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL1246082 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL22019046 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL29471996 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400290-A1 | 5-Amino-4-hydroxyvalerianic acid derivatives useful as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |