Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757447 | 0.84 | LOXL2 (0.64) | SLC7A5CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL10431445 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL12301533 | 0.84 | SLC7A5 (0.65) | SLC7A5LOXL2CYP4F2CYP4A11CYP2C19 | |
| SCHEMBL3499880 | 0.83 | SLC7A5 (0.63) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL7384982 | 0.83 | SLC7A5 (0.63) | SLC7A5TDP1LOXL2CYP4F2CYP4A11 | |
| SCHEMBL3293258 | 0.82 | CYP4F2 (0.61) | CYP3A4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL28813161 | 0.81 | MEN1 (0.48) | SLC7A5CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL4928282 | 0.81 | LOXL2 (0.69) | SLC7A5LOXL2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL22019046 | 0.81 | SLC7A5 (0.62) | SLC7A5TDP1LOXL2CYP4F2CYP4A11 | |
| SCHEMBL127411 | 0.81 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | SLC7A5 520/4885CYP3A4 1622/4885MEN1 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.