Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 3/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953659 | 0.96 | ALDH1A1 (0.69) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL17198419 | 0.90 | ALDH1A1 (0.80) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL29558108 | 0.90 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL22333992 | 0.90 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL22901905 | 0.90 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL9370557 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDSLC6A2TACR2NT5E | |
| SCHEMBL20830104 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDSLC6A2TACR2NT5E | |
| SCHEMBL13396743 | 0.86 | ALDH1A1 (0.73) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL26206934 | 0.85 | ALDH1A1 (0.72) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL26207249 | 0.85 | ALDH1A1 (0.75) | ALDH1A1HPGDPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391411-A2 | 3'-Substituted methyl nucleosides as antiviral agents | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | disclosed |