Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 3/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901905 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL29558108 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL4953659 | 0.92 | ALDH1A1 (0.69) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL10432003 | 0.90 | ALDH1A1 (0.66) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL26209791 | 0.89 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL26209710 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL17198419 | 0.86 | ALDH1A1 (0.80) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL22333926 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDPOLBSLC6A2KMT2A | |
| SCHEMBL22333927 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDPOLBSLC6A2KMT2A | |
| SCHEMBL17198635 | 0.84 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340613-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE | IMMUNESENSOR THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |
| US-11213592-B2 | Antibody-sting agonist conjugates and their use in immunotherapy | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2022-01-04 | — | — | US | disclosed |
| US-20210290774-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | US | disclosed |
| US-11033635-B2 | Antibody-STING agonist conjugates and their use in immunotherapy | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| WO-2021016204-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-01-28 | — | — | WO | disclosed |
| US-20210015941-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | US | disclosed |
| EP-3692996-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE | Immune Sensor, LLC (US) | 2020-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11213592-B2 | Antibody-sting agonist conjugates and their use in immunotherapy | STING1, CGAS, MAVS | ALDH1A1 4589/4885HPGD 3490/4885POLB 1958/4885 |
| US-20210290774-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | STING1, CGAS, MAVS | ALDH1A1 4589/4885HPGD 3490/4885POLB 1958/4885 |
| US-20220340613-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE | CGAS, PDE7A, PDE11A | ALDH1A1 3411/4885HPGD 201/4885POLB 100/4885 |
| US-11033635-B2 | Antibody-STING agonist conjugates and their use in immunotherapy | STING1, CGAS, MAVS | ALDH1A1 4589/4885HPGD 3490/4885POLB 1958/4885 |
| US-20210015941-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | STING1, CGAS, MAVS | ALDH1A1 4589/4885HPGD 3490/4885POLB 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.