Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296754 | 0.92 | CTSK (0.57) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL7294855 | 0.90 | CTSK (0.52) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL10432035 | 0.85 | CTSK (0.52) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL8353955 | 0.82 | CTSK (0.62) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL14011286 | 0.81 | CTSK (0.64) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL10432273 | 0.81 | CTSK (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10431940 | 0.81 | CTSK (0.48) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL7292473 | 0.80 | CTSK (0.60) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL7434135 | 0.80 | SYK (0.54) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL8276388 | 0.80 | CTSK (0.56) | CTSKCTSLCTSSCTSBPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362002-A1 | HIV protease inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |