Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433268 | 1.00 | CTSD (0.51) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL6832634 | 0.87 | ALDH1A1 (0.53) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL7882872 | 0.87 | ALDH1A1 (0.53) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL7771093 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTLMNACYP3A4 | |
| SCHEMBL7771089 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTLMNACYP3A4 | |
| SCHEMBL6379911 | 0.77 | TSHR (0.50) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL6379914 | 0.77 | TSHR (0.50) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL115478 | 0.76 | CTSD (0.65) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL10766788 | 0.76 | CTSD (0.65) | CTSDALDH1A1TSHRMAPTLMNA | |
| SCHEMBL8397874 | 0.75 | HPGD (0.53) | ALDH1A1TSHRMAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |