⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20499392 | 0.67 | — | — | |
| SCHEMBL18687593 | 0.63 | — | — | |
| SCHEMBL710129 | 0.63 | — | — | |
| SCHEMBL20541953 | 0.62 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL21331900 | 0.62 | — | — | |
| SCHEMBL6065583 | 0.60 | — | — | |
| SCHEMBL5963506 | 0.58 | — | — | |
| SCHEMBL17233963 | 0.55 | — | — | |
| SCHEMBL21385228 | 0.53 | — | — | |
| SCHEMBL8377720 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764082-B1 | 4-5-diamino-N,N-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | OREAL (FR) | 2011-06-29 | — | — | EP | claimed |
| EP-1550656-B1 | fused 4-5-diamino-n,n-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | OREAL (FR) | 2009-05-06 | — | — | EP | claimed |
| US-7285137-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | claimed |
| US-20050166335-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2005-08-04 | — | — | US | claimed |
| EP-0037344-B1 | AMINO-ALCOXY PYRAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1984-07-11 | — | — | EP | claimed |
| CN-115448922-A | Free base crystal form containing pyrazole polycyclic derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-12-09 | — | — | CN | disclosed |
| EP-2274340-B1 | PIGMENT DISPERSER AND EASILY DISPERSED SOLID PIGMENT PREPARATIONS | CLARIANT FINANCE BVI LTD (VG) | 2012-05-16 | — | — | EP | disclosed |
| EP-2274340-A1 | PIGMENT DISPERSER AND EASILY DISPERSED SOLID PIGMENT PREPARATIONS | Clariant Finance (BVI) Limited (VG) | 2011-01-19 | — | — | EP | disclosed |
| US-7642360-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2010-01-05 | — | — | US | disclosed |
| US-7642360-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2010-01-05 | — | — | US | disclosed |
| WO-2009132738-A1 | PIGMENT DISPERSER AND EASILY DISPERSED SOLID PIGMENT PREPARATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2009-11-05 | — | — | WO | disclosed |
| US-20080071092-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| US-7285137-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7285137-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| US-20050166335-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2005-08-04 | — | — | US | disclosed |
| US-20050166335-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2005-08-04 | — | — | US | disclosed |
| EP-1259510-A2 | TRICYCLIC DIHYDROPYRAZOLONE AND TRICYCLIC DIHYDROISOXAZOLONE POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001066544-A2 | TRICYCLIC DIHYDROPYRAZOLONE AND TRICYCLIC DIHYDROISOXAZOLONE POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |
| EP-0185248-B1 | POLYADDITION OR POLYCONDENSATION PRODUCTS, THEIR AQUEOUS DISPERSIONS AS WELL AS A PHOTOGRAPHIC RECORDING MATERIAL CONTAINING A PHOTOGRAPHIC COMPOUND IN THE FORM OF SUCH POLYMERIC PRODUCTS | Agfa-Gevaert AG (DE) | 1990-10-03 | — | — | EP | disclosed |
| EP-0185248-A2 | Polyaddition or polycondensation products, their aqueous dispersions as well as a photographic recording material containing a photographic compound in the form of such polymeric products | Agfa-Gevaert AG (DE) | 1986-06-25 | — | — | EP | disclosed |