SCHEMBL710129

SCHEMBL710129

Nn1ccc(=O)[nH]c1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27496234 0.98 CRBN (0.95)
SCHEMBL27714028 0.77 CRBN (0.59)
SCHEMBL6065583 0.76
SCHEMBL5963506 0.75
SCHEMBL438290 0.70
SCHEMBL422813 0.70
SCHEMBL10423652 0.70
SCHEMBL21385228 0.70
SCHEMBL8790967 0.70
SCHEMBL8377720 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144792-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS SOCPRA SCIENCES SANTÉ HUMAINES S.E.C. (CA) 2026-05-28 US claimed
US-20250302837-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2025-10-02 US claimed
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
EP-4504201-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS Socpra Sciences Santé Et Humaines S.E.C. (CA) 2025-02-12 EP claimed
CN-119278042-A Chymase inhibitors for selective dissolution of thrombi in thrombotic or thromboembolic disorders 索克普拉健康与人文科学公司 2025-01-07 CN claimed
CN-118956255-A Photo-curing self-repairing coating and preparation method thereof 无锡海特新材料研究院有限公司 2024-11-15 CN claimed
CN-118027538-A Calcium acrylate-based environment-friendly stabilizer, preparation method and application thereof in PVC-M (polyvinyl chloride-M) pipe 甘肃青龙管业有限责任公司 2024-05-14 CN claimed
WO-2023194222-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS SOCPRA SCIENCES SANTÉ HUMAINES S.E.C. (CA) 2023-10-12 WO claimed
CN-116181200-A Wood-plastic door and production process thereof 江苏美乐嘉科技新材料有限公司 2023-05-30 CN claimed
CN-113788924-B Polyurethane elastomer and preparation method thereof 重庆文理学院 2022-12-06 CN claimed
CN-1832994-A Novel stabilizing system for halogen-containing polymers CROMPTON VINYL ADDITIVES GMBH (DE) 2006-09-13 CN claimed
CN-1780878-A stabilizer system for stabilizing halogenated polymers CROMPTON VINYL ADDITIVES GMBH (DE) 2006-05-31 CN claimed
CN-1757665-A Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2006-04-12 CN claimed
CN-1711076-A Combination cancer therapy of a GST-activated anticancer compound and another anticancer therapy TELIK INC (US) 2005-12-21 CN claimed
CN-1500118-A Use of substituted biaromatic beta-diketone as stabilising agent of halogenated polymers and resulting polymer �޵��ǻ�ѧ��˾ 2004-05-26 CN claimed
CN-1440439-A Method for stabilising halogenated polymers by means of pyrroles or derivatives thereof and compositions containing same RHODIA CHIMIE SA (FR) 2003-09-03 CN claimed
CN-1108293-C Substituted 1-amino-3-phenyluracil derivatives, their preparation and their use as herbicides BAYER AG (DE) 2003-05-14 CN claimed
CN-1270583-A Substituted phenyluracils BAYER AG (DE) 2000-10-18 CN claimed
CN-1195341-A Substituted 1-amino-3-phenyluracil derivatives, their preparation and their use as herbicides BAYER AG (DE) 1998-10-07 CN claimed
US-5801181-A Amino alcohol substituted cyclic compounds CELL THERAPEUTICS, INC. (US) 1998-09-01 US claimed