⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710129 | 0.76 | — | — | |
| SCHEMBL5792152 | 0.74 | CRBN (0.42) | — | |
| SCHEMBL8652644 | 0.73 | — | — | |
| SCHEMBL7546869 | 0.68 | CRBN (0.41) | — | |
| SCHEMBL11582823 | 0.68 | CRBN (0.41) | — | |
| SCHEMBL14936971 | 0.67 | CRBN (0.35) | — | |
| SCHEMBL10431532 | 0.66 | MAPT (0.37) | — | |
| SCHEMBL41240 | 0.66 | PKM (0.42) | — | |
| SCHEMBL9426408 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL1673256 | 0.65 | KMT2A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4074171-A | — | — | None | — | — | JP | disclosed |
| CN-103917529-A | 2-thiopyrimidinones | PFIZER | 2014-07-09 | — | — | CN | disclosed |
| EP-1560878-B1 | THERMALLY STABILISED PVC COMPOSITIONS | LAMBERTI SPA (IT) | 2006-05-17 | — | — | EP | disclosed |
| EP-1560878-A1 | THERMALLY STABILISED PVC COMPOSITIONS | Lamberti Spa (IT) | 2005-08-10 | — | — | EP | disclosed |
| EP-1174461-B1 | Thermally stabilized PVC compositions | LAMBERTI SPA (IT) | 2004-10-27 | — | — | EP | disclosed |
| US-6790885-B2 | CHLORINE CONTAINING POLYMER COMPOSITIONS CONTAINING STABILIZERS WHICH IMPART GOOD THERMAL STABILITY. PVC COMPOSITIONS AND, IN PARTICULAR, FLEXIBLE PVC COMPOSITIONS CONTAINING STABILIZERS WHICH ARE OLIGOMERIC AND/OR POLYMERIC | LAMBERTI SPA (IT) | 2004-09-14 | — | — | US | disclosed |
| WO-2004046236-A1 | THERMALLY STABILISED PVC COMPOSITIONS | LAMBERTI SPA (IT) | 2004-06-03 | — | — | WO | disclosed |
| US-20030109607-A1 | Thermally stabilized polyvinyl chloride compositions | LAMBERTI SPA (IT) | 2003-06-12 | — | — | US | disclosed |
| EP-1174461-A1 | Thermally stabilized PVC compositions | LAMBERTI S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| JP-H0474171-A | THIOAMINOURACIL COMPOUND | YAMASA SHOYU CO LTD | 1992-03-09 | — | — | JP | disclosed |