Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543292 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL10477079 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTCYP3A4MAPTLMNA | |
| SCHEMBL1662886 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL1318602 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL11777721 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL7290850 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL7290847 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL9474405 | 0.76 | CASP6 (0.52) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL7471511 | 0.75 | MAPT (0.50) | ALDH1A1HTTTSHRCYP3A4MAPT | |
| SCHEMBL6677275 | 0.75 | MAPT (0.73) | ALDH1A1HTTTSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373216-A1 | CEPHALOSPORIN COMPOUNDS OR THEIR SALTS, PROCESS FOR THEIR PREPARATION, AND PARMACEUTICAL COMPOSITIONS | TEIJIN LIMITED (JP) | 1990-06-20 | — | — | EP | disclosed |
| EP-0347459-A1 | CEPHALOSPORIN COMPOUNDS OR THEIR SALTS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS | TEIJIN LIMITED (JP) | 1989-12-27 | — | — | EP | disclosed |