Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433607 | 0.85 | PPARD (0.40) | MAPK14CETPPPARGPPARDPPARA | |
| Halfenprox SCHEMBL29795788 | 0.80 | NPC1 (0.43) | MAPK14NPC1POLBCYP2C9RAB9A | |
| Halfenprox SCHEMBL62803 | 0.80 | NPC1 (0.43) | MAPK14NPC1POLBCYP2C9RAB9A | |
| SCHEMBL4926133 | 0.79 | FDFT1 (0.43) | MAPK14NPC1POLBCYP2C9RAB9A | |
| SCHEMBL10433605 | 0.79 | MAPK14 (0.41) | MAPK14NPC1POLBCYP2C9RAB9A | |
| SCHEMBL2765311 | 0.78 | CETP (0.41) | MAPK14NPC1POLBCYP2C9RAB9A | |
| SCHEMBL2765313 | 0.77 | NPC1 (0.43) | MAPK14NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9839259 | 0.76 | ALDH1A1 (0.50) | NPC1CYP2C9KDM4EALDH1A1HTT | |
| SCHEMBL8321421 | 0.74 | MAPK14 (0.48) | MAPK14CETPPPARGPPARDPPARA | |
| SCHEMBL8321423 | 0.74 | MAPK14 (0.48) | MAPK14CETPPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393513-A1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-24 | — | — | EP | disclosed |