SCHEMBL2765313

SCHEMBL2765313

CCC(C)(CCc1cccc(Oc2ccccc2)c1)c1ccc(OC(F)(F)Br)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
RAB9A P51151 1/20 0.43
MAPK14 Q16539 2/20 0.39
CETP P11597 6/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FDFT1 P37268 3/20 0.37
PPARG P37231 2/20 0.37
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37
AKR1C3 P42330 1/20 0.36
P2RX3 P56373 1/20 0.36
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433605 0.86 MAPK14 (0.41) NPC1POLBCYP2C9RAB9AMAPK14
SCHEMBL4926133 0.84 FDFT1 (0.43) NPC1POLBCYP2C9RAB9AMAPK14
SCHEMBL10544536 0.83 FDFT1 (0.46) NPC1POLBCYP2C9RAB9AKDM4E
SCHEMBL10549355 0.83 CETP (0.47) CETPFDFT1
SCHEMBL10547464 0.81 FDFT1 (0.47) NPC1POLBCYP2C9RAB9AMAPK14
SCHEMBL9558003 0.79 FDFT1 (0.46) NPC1POLBCYP2C9RAB9AKDM4E
SCHEMBL10543647 0.79 CETP (0.42) NPC1POLBCYP2C9RAB9AMAPK14
SCHEMBL9558187 0.79 KDM4E (0.50) NPC1POLBCYP2C9RAB9AKDM4E
SCHEMBL10547498 0.79 FDFT1 (0.49) NPC1POLBCYP2C9RAB9AKDM4E
SCHEMBL10547619 0.78 LTA4H (0.49) NPC1POLBCYP2C9RAB9ACETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163110-B2 Granule coated with urethane resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-20 US disclosed
US-20100151250-A1 GRANULE COATED WITH URETHANE RESIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-17 US disclosed
EP-1846145-B1 MIXING APPARATUS AND METHOD SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-20060062819-A1 Enveloped pesticidal formulations SUMITOMO CHEMICAL COMPANY, LIMITED 2006-03-23 US disclosed
US-6998132-B1 Enveloped pesticidal formulations SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-14 US disclosed
EP-1005792-B1 PACKAGED PESTICIDE PREPARATIONS SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed
EP-1166630-B1 Solid pesticidal formulation SUMITOMO CHEMICAL CO (JP) 2003-07-09 EP disclosed
US-20020019441-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-14 US disclosed
EP-1166630-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-02 EP disclosed
EP-1005792-A1 PACKAGED PESTICIDE PREPARATIONS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-07 EP disclosed