Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562062 | 0.76 | CA2 (0.58) | CA2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL898388 | 0.76 | CA2 (0.58) | CA2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL411517 | 0.76 | CA2 (0.58) | CA2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28511826 | 0.72 | MEN1 (0.46) | CA2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2115284 | 0.72 | CRBN (0.45) | CA2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2115280 | 0.72 | CRBN (0.45) | CA2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6041975 | 0.71 | CA2 (0.49) | CA2CA12CA9KMT2AMEN1 | |
| SCHEMBL27802097 | 0.71 | CRBN (0.44) | CA2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL879857 | 0.69 | CA2 (0.46) | CA2CA12CA9KMT2AMEN1 | |
| SCHEMBL4294384 | 0.69 | CA2 (0.46) | CA2CA12CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |