Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898388 | 0.86 | CA2 (0.58) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL411517 | 0.86 | CA2 (0.58) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL562062 | 0.86 | CA2 (0.58) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL879857 | 0.84 | CA2 (0.46) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL2724163 | 0.84 | CA2 (0.46) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL3490631 | 0.84 | CA2 (0.46) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL23827433 | 0.82 | CA2 (0.44) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL9281309 | 0.82 | CA2 (0.44) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL7165666 | 0.81 | CA2 (0.43) | CA2ALDH1A1NPSR1CYP3A4KDM4E | |
| SCHEMBL23540262 | 0.81 | CA2 (0.43) | CA2ALDH1A1NPSR1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270469-A1 | SUBSTITUTED OXAZOLIDINONES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090270469-A1 | SUBSTITUTED OXAZOLIDINONES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270469-A1 | SUBSTITUTED OXAZOLIDINONES | MUSK, MYLK2, PYGM | CA2 488/4885ALDH1A1 2157/4885NPSR1 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.