Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433895 | 1.00 | KMT2A (0.32) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10433791 | 1.00 | KMT2A (0.32) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10433893 | 1.00 | KMT2A (0.32) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8979373 | 0.90 | CHEK1 (0.33) | KMT2ACHEK1GSTP1GSTM2MEN1 | |
| SCHEMBL8979395 | 0.90 | CHEK1 (0.33) | KMT2ACHEK1GSTP1GSTM2MEN1 | |
| SCHEMBL8979393 | 0.90 | CHEK1 (0.33) | KMT2ACHEK1GSTP1GSTM2MEN1 | |
| SCHEMBL8979374 | 0.90 | CHEK1 (0.33) | KMT2ACHEK1GSTP1GSTM2MEN1 | |
| SCHEMBL8979375 | 0.90 | CHEK1 (0.33) | KMT2ACHEK1GSTP1GSTM2MEN1 | |
| SCHEMBL10434335 | 0.89 | ALDH1A1 (0.34) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10434337 | 0.89 | ALDH1A1 (0.34) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |