Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979393 | 1.00 | CHEK1 (0.33) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL8979375 | 1.00 | CHEK1 (0.33) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL8979373 | 1.00 | CHEK1 (0.33) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL8979374 | 1.00 | CHEK1 (0.33) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL10433892 | 0.90 | KMT2A (0.32) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL10433791 | 0.90 | KMT2A (0.32) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL10433893 | 0.90 | KMT2A (0.32) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL10433895 | 0.90 | KMT2A (0.32) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL10434337 | 0.83 | ALDH1A1 (0.34) | CHEK1GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL10434335 | 0.83 | ALDH1A1 (0.34) | CHEK1GSTP1GSTM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5312999-A | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |