Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433972 | 1.00 | VCAM1 (0.34) | VCAM1TDP1MAPTPKMSRD5A2 | |
| SCHEMBL10434038 | 1.00 | VCAM1 (0.34) | VCAM1TDP1MAPTPKMSRD5A2 | |
| SCHEMBL10434005 | 0.88 | VCAM1 (0.35) | VCAM1TDP1MAPTPKMSRD5A2 | |
| SCHEMBL10433856 | 0.88 | VCAM1 (0.35) | VCAM1TDP1MAPTPKMSRD5A2 | |
| SCHEMBL10433857 | 0.88 | VCAM1 (0.35) | VCAM1TDP1MAPTPKMSRD5A2 | |
| SCHEMBL10434115 | 0.81 | TDP1 (0.38) | VCAM1TDP1MAPTSRD5A2SMN1; SMN2 | |
| SCHEMBL10433794 | 0.81 | TDP1 (0.38) | TDP1MAPTSRD5A2SMN1; SMN2POLB | |
| SCHEMBL10434223 | 0.81 | TDP1 (0.38) | TDP1MAPTSRD5A2SMN1; SMN2POLB | |
| SCHEMBL10434114 | 0.81 | TDP1 (0.38) | VCAM1TDP1MAPTSRD5A2SMN1; SMN2 | |
| SCHEMBL10433795 | 0.81 | TDP1 (0.38) | TDP1MAPTSRD5A2SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |