Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434223 | 1.00 | TDP1 (0.38) | TDP1SMN1; SMN2EPAS1ALDH1A1MAPT | |
| SCHEMBL10433794 | 1.00 | TDP1 (0.38) | TDP1SMN1; SMN2EPAS1ALDH1A1MAPT | |
| SCHEMBL10434115 | 0.86 | TDP1 (0.38) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 | |
| SCHEMBL10434114 | 0.86 | TDP1 (0.38) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 | |
| SCHEMBL8979401 | 0.86 | LMNA (0.39) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 | |
| SCHEMBL1496810 | 0.86 | LMNA (0.39) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 | |
| SCHEMBL2923101 | 0.86 | LMNA (0.39) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 | |
| SCHEMBL25222043 | 0.81 | MAPT (0.44) | TDP1SMN1; SMN2ALDH1A1MAPTS1PR4 | |
| SCHEMBL10434038 | 0.81 | VCAM1 (0.34) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 | |
| SCHEMBL10433971 | 0.81 | VCAM1 (0.34) | TDP1SMN1; SMN2ALDH1A1MAPTSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |