⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369902 | 0.97 | ALDH1A1 (0.47) | — | |
| SCHEMBL104545 | 0.97 | ALDH1A1 (0.47) | — | |
| SCHEMBL19705361 | 0.97 | ALDH1A1 (0.47) | — | |
| SCHEMBL7776775 | 0.97 | ALDH1A1 (0.47) | — | |
| SCHEMBL278463 | 0.97 | ALDH1A1 (0.47) | — | |
| SCHEMBL23319723 | 0.97 | GAA (0.46) | — | |
| SCHEMBL19966112 | 0.97 | ALDH1A1 (0.47) | — | |
| SCHEMBL18844888 | 0.97 | ALDH1A1 (0.47) | — | |
| Fluoride SCHEMBL7235974 | 0.94 | ALDH1A1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL2863718 | 0.94 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292604-B1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LTD (GB) | 2009-05-13 | — | — | EP | claimed |
| CN-1810822-A | 2-aminocarbonyl-9h-purine derivatives | PFIZER (US) | 2006-08-02 | — | — | CN | claimed |
| CN-1249074-C | 2-aminocarbonyl-9H-purine derivatives | PFIZER LTD (US) | 2006-04-05 | — | — | CN | claimed |
| US-6753322-B2 | 2-aminocarbonyl-9H-purine derivatives | PFIZER INC | 2004-06-22 | — | — | US | claimed |
| US-20040077584-A1 | 2-Aminocarbonyl-9H-purine derivatives | PFIZER INC | 2004-04-22 | — | — | US | claimed |
| CN-1434830-A | 2-aminocarbonyl-9H-purine derivatives | PFIZER LTD (US) | 2003-08-06 | — | — | CN | claimed |
| EP-1292604-A1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | Pfizer Limited (GB) | 2003-03-19 | — | — | EP | claimed |
| US-20020058641-A1 | 2-aminocarbonyl-9H-purine derivatives | PFIZER INC. | 2002-05-16 | — | — | US | claimed |
| WO-2001094368-A1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-12-13 | — | — | WO | claimed |
| CN-118956250-B | High-strength high-weather-resistance elastic coating and preparation method and application thereof | 天津森聚柯密封涂层材料有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118956250-A | High-strength high-weather-resistance elastic coating and preparation method and application thereof | 天津森聚柯密封涂层材料有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118834594-A | Single-component elastic coating and preparation method and application thereof | 沧州渤海新区高内聚能化工有限公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20240018150-A1 | SMALL MOLECULAR INHIBITOR AGAINST BTK AND/OR BTK C481S AND USE THEREOF | ARROMAX PHARMATECH CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| US-11814391-B2 | Macrocyclic compounds for the treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| EP-0680478-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994017063-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | disclosed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | disclosed |