Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104545 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL19705361 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL22369902 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL7776775 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL18844888 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL278463 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL23319701 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL2863718 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| Fluoride SCHEMBL7235974 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HSD17B10GAAL3MBTL1ATM | |
| SCHEMBL1440206 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HSD17B10GAAL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468997-B1 | TREATMENT OF IGG4-RELATED DISEASES WITH ANTI-CD19 ANTIBODIES CROSSBINDING TO CD32B | XENCOR INC (US) | 2023-09-13 | — | — | EP | disclosed |
| US-11027242-B2 | Nanofiltration membranes and methods of use | NOVOMER, INC. (US) | 2021-06-08 | — | — | US | disclosed |
| US-10011616-B2 | Boron-containing small molecules as antiprotozoal1 agents | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2018-07-03 | — | — | US | disclosed |
| US-20180072760-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOALl AGENTS | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011616-B2 | Boron-containing small molecules as antiprotozoal1 agents | HBS1L, DBNL, BOD1L1 | ALDH1A1 3991/4885HSD17B10 4030/4885GAA 121/4885 |
| US-20180072760-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOALl AGENTS | ABCB11, ABCB7, BRI3BP | ALDH1A1 4268/4885HSD17B10 4224/4885GAA 131/4885 |
| US-11027242-B2 | Nanofiltration membranes and methods of use | MLEC, EPCAM, LNPK | ALDH1A1 1130/4885HSD17B10 3295/4885GAA 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.