SCHEMBL10434650

SCHEMBL10434650

CC1(C)CC(NNC(=O)CCC(N)=O)CC(C)(C)N1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
HTT P42858 1/20 0.42
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 3/20 0.38
EZH2 Q15910 4/20 0.37
RECQL P46063 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 1/20 0.36
USP2 O75604 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10434663 0.87 HTT (0.43) GAAHTTKMT2AKDM4EPOLB
SCHEMBL7766498 0.84 GAA (0.61) GAAHTTKMT2AKDM4EPOLB
SCHEMBL10434871 0.80 KDM4E (0.30) KDM4E
SCHEMBL9031634 0.79 EPHX2 (0.47) GAAHTTKMT2AKDM4EMEN1
SCHEMBL817042 0.77 POLB (0.41) GAAHTTKMT2AKDM4EPOLB
SCHEMBL8088104 0.76 GAA (0.60) GAAHTTKMT2AKDM4EPOLB
SCHEMBL2901212 0.74 GAA (0.71) GAAHTTKMT2AKDM4EPOLB
SCHEMBL10559499 0.72 GAA (0.63) GAAHTTKMT2AKDM4EPOLB
SCHEMBL8334264 0.71 GAA (0.61) GAAHTTKMT2AKDM4EPOLB
SCHEMBL9150541 0.71 GAA (0.57) GAAHTTKMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366057-A2 Light stabilizing flame retardants ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1990-05-02 EP disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed