Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932656 | 0.85 | MEN1 (0.33) | KDM4EALDH1A1IDO1NPC1RAB9A | |
| SCHEMBL11803023 | 0.85 | NPC1 (0.34) | KDM4EALDH1A1NOTUMIDO1NPC1 | |
| SCHEMBL9862309 | 0.83 | MEN1 (0.36) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29409495 | 0.80 | — | — | |
| SCHEMBL114436 | 0.80 | — | — | |
| SCHEMBL2650416 | 0.77 | ESR2 (0.48) | KDM4EALDH1A1CYP11B1CYP11B2GABRA1 | |
| SCHEMBL29547174 | 0.77 | ACHE (0.47) | KDM4EALDH1A1NOTUMIDO1NPC1 | |
| SCHEMBL197834 | 0.77 | ACHE (0.47) | KDM4EALDH1A1NOTUMIDO1NPC1 | |
| SCHEMBL9069185 | 0.76 | ESR2 (0.47) | KDM4EALDH1A1MEN1KMT2ACYP11B1 | |
| SCHEMBL23151873 | 0.74 | CYP2A6 (0.46) | KDM4EALDH1A1NOTUMIDO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370153-A1 | Improvement process for debrominative rearrangements | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-30 | — | — | EP | disclosed |