SCHEMBL114436

SCHEMBL114436

C#Cc1ccccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29409495 1.00
SCHEMBL28504938 0.87 CYP11B1 (0.37)
SCHEMBL10434697 0.80 KDM4E (0.34)
Methanesulfonic Acid Methyl Ester SCHEMBL28827049 0.80 USP2 (0.36)
SCHEMBL31285235 0.79 CES2 (0.38)
SCHEMBL2783567 0.79 CES2 (0.38)
SCHEMBL28870 0.78 HDAC8 (0.36)
SCHEMBL29549283 0.78 HDAC8 (0.36)
SCHEMBL28351566 0.77 ALDH1A1 (0.41)
SCHEMBL29251289 0.77 GRM5 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 691 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059955-A Imidazo pyridone compound, photocatalysis continuous synthesis method and application thereof 南京工业大学 2026-05-19 CN claimed
CN-119708067-A Carbazolyl-containing C≡N cyclometalated platinum (II) complex and preparation method and application thereof 新疆大学 2025-03-28 CN claimed
CN-116102608-B Stigmasterol triazole derivative and preparation method and application thereof 郑州工程技术学院 2025-03-28 CN claimed
CN-115872993-B Method for continuously synthesizing piperidone by photoinduction 南京工业大学 2024-12-10 CN claimed
CN-115369429-B Selective borohydride reaction method for electrochemically catalyzing alkyne 南京林业大学 2024-11-08 CN claimed
CN-118420615-A Method for synthesizing pyridoquinazolinone compound by photo-induced organic catalysis alkyne difunctional cyclization 南京工业大学 2024-08-02 CN claimed
CN-117886829-A Pyridoisocoumarin compound and preparation method and application thereof 河北中烟工业有限责任公司 2024-04-16 CN claimed
CN-117646229-A Method for preparing ammonia by catalyzing NO through ultra-small copper nanoclusters 广州惠清环保技术有限公司 2024-03-05 CN claimed
CN-115337945-B Photocatalyst, preparation method thereof and application of photocatalyst in preparation of olefin compounds 中国科学院化学研究所 2024-02-20 CN claimed
EP-4021904-B1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2024-01-03 EP claimed
EP-1571150-A1 Process for the preparation of tryptase inhibitors Aventis Pharma Deutschland GmbH (DE) 2005-09-07 EP claimed
JP-2005524240-A 2005-08-11 JP claimed
EP-1244617-B1 SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE ORTHO MCNEIL PHARM INC (US) 2005-02-16 EP claimed
US-6852474-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2005-02-08 US claimed
EP-1502292-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2005-02-02 EP claimed
EP-1144403-B1 SUBSTITUTED PYRAZOLES AS P38 KINASE INHIBITORS SEARLE LLC (US) 2004-10-06 EP claimed
US-20030224586-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-12-04 US claimed
WO-2003094213-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-11-13 WO claimed
EP-0328830-B1 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds OHMEDA PHARMA PROD (US) 1994-06-01 EP claimed
EP-0160422-B1 N-ARYL-N-(4-PIPERIDINYL)AMIDES AND PHARMACEUTICAL COMPOSITIONS AND METHODS EMPLOYING SUCH COMPOUNDS Anaquest, Inc. (US) 1992-01-08 EP claimed