Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.82 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.82 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451383 | 1.00 | ESR1 (0.82) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| SCHEMBL3174260 | 1.00 | ESR1 (0.82) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| SCHEMBL833872 | 1.00 | ESR1 (0.82) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| SCHEMBL36454 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP3A4ABATKEAP1 | |
| SCHEMBL2969737 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP3A4ABATKEAP1 | |
| SCHEMBL8056670 | 0.90 | ESR1 (0.67) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| SCHEMBL7938048 | 0.90 | MMP3 (0.71) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| SCHEMBL7039574 | 0.88 | MMP3 (0.68) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| Biphenyl SCHEMBL8082690 | 0.87 | ESR1 (0.70) | ESR1ESR2MMP3BCL2L1CYP3A4 | |
| SCHEMBL18770331 | 0.86 | CYP17A1 (0.71) | ESR1ESR2CYP3A4CYP17A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356660-A1 | Aromatic polyethersulphones, process for their preparation and their use | BAYER AG (DE) | 1990-03-07 | — | — | EP | disclosed |