SCHEMBL833872

SCHEMBL833872

Oc1ccc(-c2ccc(Cc3ccc(-c4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.82
ESR2 Q92731 3/20 0.82
MMP3 P08254 1/20 0.52
BCL2L1 Q07817 1/20 0.52
CYP3A4 P08684 4/20 0.52
CYP17A1 P05093 3/20 0.52
CYP11B1 P15538 3/20 0.52
CYP11B2 P19099 3/20 0.52
ABAT P80404 1/20 0.50
KEAP1 Q14145 1/20 0.50
ABL1 P00519 1/20 0.50
ABCB1 P08183 1/20 0.50
BCR P11274 1/20 0.50
CYP19A1 P11511 2/20 0.48
CA2 P00918 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
PTPN1 P18031 1/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10434816 1.00 ESR1 (0.82) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL22451383 1.00 ESR1 (0.82) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL3174260 1.00 ESR1 (0.82) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL36454 0.91 ESR1 (1.00) ESR1ESR2CYP3A4ABATKEAP1
SCHEMBL2969737 0.91 ESR1 (1.00) ESR1ESR2CYP3A4ABATKEAP1
SCHEMBL8056670 0.90 ESR1 (0.67) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL7938048 0.90 MMP3 (0.71) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL7039574 0.88 MMP3 (0.68) ESR1ESR2MMP3BCL2L1CYP3A4
Biphenyl SCHEMBL8082690 0.87 ESR1 (0.70) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL18770331 0.86 CYP17A1 (0.71) ESR1ESR2CYP3A4CYP17A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257887-B1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECH CO (SA) 2024-11-06 EP claimed
US-20190233586-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. 2019-08-01 US claimed
EP-3486269-A1 POLYMERIZATION SYSTEM FOR THE COPOLYMERIZATION OF CO2 AND EPOXIDES AND RELATED METHOD SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2019-05-22 EP claimed
US-20180022869-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. 2018-01-25 US claimed
EP-3257887-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-12-20 EP claimed
US-20170260389-A1 POLYESTER CO-PHOSPHONATES FRX POLYMERS, INC. 2017-09-14 US claimed
EP-3137444-A2 ALKOXY POLYCARBONATES, BISPHENOL MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC Global Technologies B.V. (NL) 2017-03-08 EP claimed
US-20170051106-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-02-23 US claimed
US-20160264728-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-09-15 US claimed
WO-2015168225-A2 ALKOXY POLYCARBONATES, BISPHENOL MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-05 WO claimed
US-20140000751-A1 POLYESTER CO-PHOSPHONATES DOSKOCIL MANUFACTURING COMPANY, INC. 2014-01-02 US claimed
US-8604155-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2013-12-10 US claimed
WO-2013177546-A2 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-11-28 WO claimed
WO-2013154349-A1 SODIUM SECONDARY BATTERY SK INNOVATION CO.,LTD. (KR) 2013-10-17 WO claimed
US-20130244864-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-09-19 US claimed
US-20130066044-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-03-14 US claimed
EP-2337809-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS Novomer, Inc. (US) 2011-06-29 EP claimed
EP-1237844-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES Celgro (US) 2002-09-11 EP claimed
WO-2001044162-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES CELGRO (US) 2001-06-21 WO claimed
US-4775739-A IMPROVED FLOWABILITY MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-10-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260389-A1 POLYESTER CO-PHOSPHONATES PHOSPHO1, PNKP, PHYKPL ESR1 2108/4885ESR2 3634/4885MMP3 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.