Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434830 | 0.93 | TSHR (0.39) | RARBTP53TSHRCNR2 | |
| SCHEMBL27989443 | 0.83 | THRB (0.38) | TSHRPTPN11CNR2 | |
| SCHEMBL10596237 | 0.81 | NR5A1 (0.38) | RARB | |
| SCHEMBL10596280 | 0.81 | NR5A1 (0.38) | RARB | |
| SCHEMBL10526390 | 0.81 | RARB (0.42) | RARBPTPN11 | |
| SCHEMBL7370067 | 0.78 | RARB (0.44) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10448680 | 0.78 | RARB (0.47) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10598385 | 0.77 | USP2 (0.35) | — | |
| SCHEMBL5828435 | 0.76 | CHRM2 (0.39) | RARBTP53TSHRCNR2 | |
| SCHEMBL4186206 | 0.76 | CHRM2 (0.39) | RARBTP53TSHRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |