Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345696 | 0.84 | RARB (0.43) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10445848 | 0.82 | NR5A1 (0.41) | RARBTP53TSHRPLA2G4B | |
| SCHEMBL9842930 | 0.80 | POLM (0.40) | — | |
| SCHEMBL8969959 | 0.80 | FAAH (0.47) | RARBTP53TSHRPLA2G4BNFKB1 | |
| SCHEMBL10449057 | 0.79 | NR5A1 (0.40) | TSHRLMNA | |
| SCHEMBL28464418 | 0.79 | NR5A1 (0.40) | TSHRLMNA | |
| SCHEMBL21224653 | 0.79 | NR5A1 (0.40) | TSHRLMNA | |
| SCHEMBL10434848 | 0.78 | RARB (0.42) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL28472097 | 0.77 | NR5A1 (0.37) | TSHR | |
| SCHEMBL8374321 | 0.74 | RARB (0.49) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |