Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804588 | 0.80 | NAAA (0.36) | NAAA | |
| SCHEMBL23518555 | 0.79 | MMP1 (0.41) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL10900634 | 0.79 | MMP1 (0.41) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL11102604 | 0.77 | NAAA (0.45) | SMN1; SMN2ALDH1A1NAAA | |
| SCHEMBL24709887 | 0.76 | MMP1 (0.38) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL23270918 | 0.76 | NAAA (0.50) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL23270922 | 0.76 | NAAA (0.46) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL872809 | 0.74 | CYP2C19 (0.53) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL23270906 | 0.74 | CYP2C19 (0.53) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL23270910 | 0.74 | CYP2C19 (0.53) | SMN1; SMN2MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |