Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089418 | 0.98 | CETP (0.49) | CETPCNR2CSNK1EMEN1KMT2A | |
| SCHEMBL6098576 | 0.87 | SLC1A3 (0.42) | CETPMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL6028474 | 0.81 | CETP (0.45) | CETPCNR2CSNK1ECTRC | |
| SCHEMBL6683665 | 0.81 | ALDH1A1 (0.47) | CETPCNR2CSNK1EALDH1A1CYP3A4 | |
| SCHEMBL2067113 | 0.80 | TSHR (0.44) | MEN1KMT2AALDH1A1TSHRMAPK1 | |
| SCHEMBL6685008 | 0.79 | ALDH1A1 (0.49) | CETPCNR2CSNK1EMEN1KMT2A | |
| SCHEMBL31470624 | 0.79 | ALDH1A1 (0.49) | CETPCNR2CSNK1EMEN1KMT2A | |
| SCHEMBL27277461 | 0.79 | ALDH1A1 (0.49) | CETPCNR2CSNK1EMEN1KMT2A | |
| SCHEMBL4552959 | 0.79 | CETP (0.43) | CETPCNR2CSNK1EALDH1A1CYP3A4 | |
| SCHEMBL2799652 | 0.79 | CSNK1E (0.50) | CETPCNR2CSNK1EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |