Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264194 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL6580103 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL6431885 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL6664894 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL3745108 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| Ethylene Glycol SCHEMBL8149806 | 0.93 | SPHK2 (0.46) | SPHK2SPHK1ALDH1A1GBA1 | |
| SCHEMBL1750705 | 0.90 | — | — | |
| SCHEMBL28897867 | 0.84 | TSHR (0.57) | SPHK2SPHK1ALDH1A1 | |
| SCHEMBL8855730 | 0.81 | ALDH1A1 (0.50) | SPHK2SPHK1ALDH1A1EPHX1 | |
| SCHEMBL5685367 | 0.81 | ALDH1A1 (0.50) | SPHK2SPHK1ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |