Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264194 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL10436732 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL6431885 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL6664894 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| SCHEMBL3745108 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1EPHX1GBA1 | |
| Ethylene Glycol SCHEMBL8149806 | 0.93 | SPHK2 (0.46) | SPHK2SPHK1ALDH1A1GBA1 | |
| SCHEMBL1750705 | 0.90 | — | — | |
| SCHEMBL28897867 | 0.84 | TSHR (0.57) | SPHK2SPHK1ALDH1A1 | |
| SCHEMBL8855730 | 0.81 | ALDH1A1 (0.50) | SPHK2SPHK1ALDH1A1EPHX1 | |
| SCHEMBL5685367 | 0.81 | ALDH1A1 (0.50) | SPHK2SPHK1ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412309-B1 | EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM | EASTMAN CHEM CO (US) | 2015-04-29 | — | — | EP | claimed |
| EP-1412309-A2 | EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM | EASTMAN CHEMICAL COMPANY (US) | 2004-04-28 | — | — | EP | claimed |
| US-6693219-B2 | PREVENTING FLUOROPHOSPHITE LIGANDS HYDROLYSIS BY ADDING AN EPOXIDE; CATALYTIC HYDROFORMYLATION OF ALPHA-OLEFIN, HYDROGEN, CARBON MONOXIDE FOR PRODUCING ALDEHYDES | EASTMAN CHEMICAL COMPANY | 2004-02-17 | — | — | US | claimed |
| US-20030018220-A1 | Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes | EASTMAN CHEMICAL COMPANY | 2003-01-23 | — | — | US | claimed |
| WO-2002098825-A2 | EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM | EASTMAN CHEMICAL COMPANY (US) | 2002-12-12 | — | — | WO | claimed |
| US-5352310-A | Forming a three-dimensional configuration by irradiating layers of polymer material to form latent image, stacking to form matrix, curing, separating | NATTER MARC D (US) | 1994-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018220-A1 | Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes | CYP2F1, CYP4F2, CYP4F11 | SPHK2 1789/4885SPHK1 1357/4885ALDH1A1 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.