Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14351521 | 0.79 | GLA (0.53) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL9427285 | 0.77 | GLA (0.53) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL9427283 | 0.77 | GLA (0.53) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL8524199 | 0.72 | HDAC3 (0.51) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL574952 | 0.72 | ALDH1A1 (0.70) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL574953 | 0.72 | ALDH1A1 (0.70) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL8607972 | 0.70 | TDP1 (0.59) | TDP1GLAMAPTLMNAPLIN1 | |
| SCHEMBL9311938 | 0.70 | CES2 (0.50) | LMNAL3MBTL1KMT2AESR1SMN1; SMN2 | |
| SCHEMBL9310242 | 0.70 | CES2 (0.50) | LMNAL3MBTL1KMT2AESR1SMN1; SMN2 | |
| SCHEMBL393959 | 0.70 | HDAC3 (0.50) | TDP1GLAMAPTLMNAPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370389-A2 | Nuclear substituted salicylic acids and their salts | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1990-05-30 | — | — | EP | disclosed |